NK/T cell lymphoma involving mediastinum: report of a case and review of literature.

نویسندگان

  • Xiang Li
  • Wei-Hua Liao
  • Jian-Hua Zhou
  • Bao-An Liu
  • Ji-Fang Wen
  • Zhong-Liang Hu
چکیده

Extranodal natural killer (NK)/T-cell lymphoma is a very aggressive malignant neoplasia with a poor prognosis. Herein we reported a case of NK/T cell lymphoma involving mediastinum. It was a 28-year-old Chinese male patient. The tumor cells were medium-sized, had irregularly folded nuclei, and inconspicuous or small nucleoli with coagulative necrosis. The tumor cells were positive for CD3ε, TIA-1, but negative for CD56. In situ hybridization revealed that tumor cells also expressed Epstein-Barr virus encoded RNA. To our knowledge, this is the first case of NK/T cell lymphoma involving mediastinum.

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عنوان ژورنال:
  • International journal of clinical and experimental pathology

دوره 7 9  شماره 

صفحات  -

تاریخ انتشار 2014